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LATEST NEWS (Archive)
2023
January 2023
JUST PUBLISHED - A population-based matched cohort study of major congenital anomalies following COVID-19 vaccination and SARS-CoV-2 infection by Clara Calvert, Jade Carruthers, Cheryl Denny, Jack Donagy, Lida E M Hopcroft, Leanne Hopkins et al. Read the article here.
December 2022
JUST PUBLISHED: Families need support to reduce the risk of adverse drug reactions from breastfeeding by Sue Jordan, Emyr Jones, Sophia Komninou, Maria Loane & Christine Damase-Michel in Pharmaceutical Journal. Read the article here.
August 2022
Women who take prescription medicines during pregnancy and breastfeeding often ask if medicines will make breastfeeding more difficult, and if medicines in breastmilk will affect their babies. As part of the ConcePTION project, we have just published a call for population databases to link data on three factors: medicine exposure; breastfeeding and infant development. This will allow the long-term impacts of medicines taken by women during pregnancy and when breastfeeding to be better understood.
Read our new publication by clicking the following link Breastfeeding, pregnancy, medicines, neurodevelopment, and population or in International Breastfeeding Journal volume 17.
March 2022
New Publication:
COVID‐19 in pregnancy—what study designs can we use to assess the risk of congenital anomalies in relation to COVID‐19 disease, treatment and vaccination? - Dolk - - Paediatric and Perinatal Epidemiology - Wiley Online Library
Jan 2022
Our group is very pleased to contribute to the influential ENCePP guide on research methods. Our SAIL work on congenital anomalies is cited as an illustration of comprehensive identification of adverse drug reactions and confounders.
Jordan S, Morris JK, Davies GI, Tucker D, Thayer DS, Luteijn JM, Morgan M, Garne E, Hansen AV, Klungsøyr K, Engeland A, Boyle B, Dolk H (2016) Selective Serotonin Reuptake Inhibitor (SSRI) antidepressants in Pregnancy and Congenital Anomalies: analysis of linked databases in Wales, Norway and Funen, Denmark. Plos One 11(12): e0165122. doi: 10.1371/journal.pone.0165122
Article Source: Selective Serotonin Reuptake Inhibitor (SSRI) Antidepressants in Pregnancy and Congenital Anomalies: Analysis of Linked Databases in Wales, Norway and Funen, Denmark
2021
June 2021
Signal Detection in EUROmediCAT: Identification and Evaluation of Medication-Congenital Anomaly Associations and Use of VigiBase as a Complementary Source of Reference. Cavadino A, Sandberg L, Öhman I, Bergvall T, Star K, Dolk H, Loane M, Addor MC, Barisic I, Cavero-Carbonell C, Garne E, Gatt M, Khoshnood B, Klungsøyr K, Latos-Bielenska A, Lelong N, Lutke R, Materna-Kiryluk A, Nelen V, Neville A, O'Mahony M, Mokoroa O, Pierini A, Randrianaivo H, Rissmann A, Tucker D, Wiesel A, Yevtushok L, Morris JK. Drug Saf. 2021 Jul;44(7):765-785. doi: 10.1007/s40264-021-01073-z. Epub 2021 May 9. PMID: 33966183.
February 2021
EUROmediCAT researchers have found that azithromycin, an antibiotic being considered for COVID-19 treatment, could be associated with increased risk of atrioventricular septal defect in babies when taken in the first trimester of pregnancy. Read the article: Macrolide and lincosamide antibiotic exposure in the first trimester of pregnancy and risk of congenital anomaly: A European case-control study
January 2021
Report of the Expert Working Group on Optimising Data on Medicines used in Pregnancy
The UK Expert Working Group included EUROmediCAT members (Rachel Charlton, Helen Dolk, Joan Morris) and can be found here: https://www.gov.uk/government/publications/report-of-the-commission-on-human-medicines-expert-working-group-on-optimising-data-on-medicines-used-during-pregnancy
2020
December 2020
Professor Sue Jordan of Swansea University and her colleagues recently published the following paper, which suggests that women who stop taking their asthma medicines during pregnancy are at risk of premature birth and are less likely to breastfeed their babies. As part of the study, the team used data from the Secure Anonymised Information Linkage (SAIL), a state-of-the-art privacy protection system, held at Swansea University and funded by the Welsh Government as part of the national research infrastructure.
Medicines prescribed for asthma, discontinuation and perinatal outcomes, including breastfeeding: A population cohort analysis Davies G, Jordan S, Thayer D, Tucker D, Humphreys I (2020) Medicines prescribed for asthma, discontinuation and perinatal outcomes, including breastfeeding: A population cohort analysis. PLOS ONE 15(12): e0242489. https://doi.org/10.1371/journal.pone.0242489
June 2020 - Update to the EUROmediSAFE inventory
As part of our work on the IMI ConcePTION Project the EUROmediSAFE inventory was updated. The Spreadsheet containing all additional Data Sources for the ConcePTION Data Source Catalogue can be found here.
This forms part of the Conception Report D1.1 Spreadsheet containing all additional Data Sources for the ConcePTION Data Source Catalogue, which is also now available for viewing and download from the ConcePTION Website by clicking here.
Risk factors for congenital heart disease: The Baby Hearts Study, a population-based case-control study. Dolk H, McCullough, N, Callaghan S, Craig B, Given J, Loane M, Lagan B, Bunting B, Boyle B, Dabir T. PLOS ONE. February 24, 2020.
Use of prescribed contraception in Northern Ireland 2010-2016. Given J, Gray A, Dolk H. The European Journal of Contraception & Reproductive Health Care. 18 Feb 2020.
Bayesian hierarchical methods in the detection of potentially teratogenic first-trimester medications. Cavadino A, Prieto-Merino D and Morris JK. Pharmacoepidemiology and Drug Safety, 6 Jan 2020.
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